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Virus dynamics: Mathematical principles of immunology and virology 1st Edition

4.0 out of 5 stars 1 customer review
ISBN-13: 978-0198504177
ISBN-10: 0198504179
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Editorial Reviews


... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host Nature

About the Author

MARTIN A. NOWAK is Professor of Biology and Mathematics at Harvard University. He is Director of the Program for Evolutionary Dynamics. In 1998 he moved to Princeton to establish the first center in Theoretical Biology at the Institute for Advanced Study. Nowak has won many prizes and has revolutionized the mathematical approach to biology. Nowak has made important contributions to the understanding of virus infections and cancer. He has pioneered the mathematical theory for the evolution of human language and altruistic behavior."Supercooperators" will be Nowak's first book for a general audience.

Robert May is Professor of Logic and Philosophy of Science, Linguistics, and Philosophy at the University of California, Irvine. Fiengo and May are the authors of Indices and Identity (MIT Press, 1994).

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Product Details

  • Paperback: 256 pages
  • Publisher: Oxford University Press; 1 edition (January 25, 2001)
  • Language: English
  • ISBN-10: 0198504179
  • ISBN-13: 978-0198504177
  • Product Dimensions: 8.9 x 0.6 x 5.9 inches
  • Shipping Weight: 1 pounds (View shipping rates and policies)
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #510,514 in Books (See Top 100 in Books)

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By Dr. Lee D. Carlson HALL OF FAMEVINE VOICE on April 8, 2001
Format: Hardcover Verified Purchase
This book is best described as the application of nonlinear ordinary differential equations to immunology and virology. It's primary emphasis is on understanding the time development of viral infections, drug treatments, and viral resistance of the HIV and hepatitis-B viruses.
The authors do a good job of describing the relevant equations needed to model virus dynamics. The book would be a good beginning for mathematicians interested in going into the field of mathematical immunology. And, even though it should be classified as a monograph, rather than a textbook, since there are no problem sets, students of mathematical immunology should find this book a useful introduction to the subject. In addition, the authors give a large list of references at the end of each chapter for further reading.
Mathematicians who need a background in the biology of the HIV virus will find a good discussion in Chapter 2 of the book. The authors give an historical summary of the origins and treatment of the virus in this chapter. This sets the stage for the mathematical modeling of virus dynamics in Chapter 3, where the authors define the basic reproductive ratio and write down a system of three coupled nonlinear ordinary differential equations as the basic equations of virus dynamics. They remark, though without justification, that an analytical solution of the time development is not possible, and so they use approximation schemes to solve the equations. The equations are a phenomenological representation of virus dynamics, and no attempt is made to relate the rate constants to the underlying microscopic properties/structures/processes of viruses.
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