I think that there's been little discussion about where we will go after the singularity occurs, as I believe it will around mid-century.
This will prove to be probably the most significant event to occur, yet few people are even considering it will happen, and even fewer are arguing what will happen in the aftermath.
You probably accept that we'll have computer-assisted brains, pretty much unlimited life, and machines that will do our inventing. But what will this do to our society?
I think it could mean an end to Capitalism. What do you give to the person who has everything? Why would such people even bother to work? Will there be open source "things" that will be designs for our build-from-atoms machines? You could download (for a fee) a design for a BMW or Lexus Personal Transportation Device, or you could take the free alternative which gets you around pretty much just as well.
Will people who face several centuries of useful life be willing to have kids? In many countries, people's kids are expected to support their parents, but if you want for very little, why procreate?
I don't think that there will be a huge gap between rich countries and poor. From what I see about AIDS in Africa, the major problem in more developed countries is a social one of people not wanting to admit that they are HIV-positive - not from there not being enough drugs at affordable prices. I would expect that the nanobots would be available to everyone in the world, unless people want massive wars.
I wonder whether we don't find aliens simply because the aliens don't care too much whether we exist or not. Imagine the disturbance that technology would bring, even if it was from 2110. If it all came at once, it would be almost impossible for us to deal with it. So maybe they treat us like we treat antiques - laughably simple, but something that you don't want to replace.
These are just a few of the ideas I have - what do you think?