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What's Going on in There? : How the Brain and Mind Develop in the First Five Years of Life Paperback – October 3, 2000
Purchase options and add-ons
how a baby's brain is "assembled" from scratch
the critical prenatal factors that shapebrain development
how the birthing process itself affects the brain
which forms of stimulation are most effective at promoting cognitive development
how boys' and girls' brains develop differently
how nutrition, stress, and other physical and social factors can permanently affect a child's brain
Brilliantly blending cutting-edge science with a mother's wisdom and insight, What's Going On in There? is an invaluable contribution to the nature versus nurture debate. Children's development is determined both by the genes they are born with and the richness of their early environment. This timely and important book shows parents the innumerable ways in which they can actually help their children grow better brains.
- Print length544 pages
- LanguageEnglish
- PublisherBantam
- Publication dateOctober 3, 2000
- Dimensions6.12 x 1.34 x 9.15 inches
- ISBN-100553378252
- ISBN-13978-0553378252
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--Publishers Weekly, starred review
From the Inside Flap
how a baby's brain is "assembled" from scratch
the critical prenatal factors that shapebrain development
how the birthing process itself affects the brain
which forms of stimulation are most effective at promoting cognitive development
how boys' and girls' brains develop differently
how nutrition, stress, and other physical and social factors can permanently affect a child's brain
Brilliantly blending cutting-edge science with a mother's wisdom and insight, What's Going On in There? is an invaluable contribution to the nature versus nurture debate. Children's development is determined both by the genes they are born with and the richness of their early environment. This timely and important book shows parents the innumerable ways in which they can actually help their children grow better brains.
From the Back Cover
how a baby's brain is "assembled" from scratch
the critical prenatal factors that shapebrain development
how the birthing process itself affects the brain
which forms of stimulation are most effective at promoting cognitive development
how boys' and girls' brains develop differently
how nutrition, stress, and other physical and social factors can permanently affect a child's brain
Brilliantly blending cutting-edge science with a mother's wisdom and insight, What's Going On in There? is an invaluable contribution to the nature versus nurture debate. Children's development is determined both by the genes they are born with and the richness of their early environment. This timely and important book shows parents the innumerable ways in which they can actually help their children grow better brains.
About the Author
Excerpt. © Reprinted by permission. All rights reserved.
Wouldn't you know it? Just as I get this beautiful, healthy neuron filled with dye and ready to image, Julia wakes up and starts crying. The experiment takes a long time to set up; I've been at it most of the day and need just ten more uninterrupted minutes. She has been so cooperative--sleeping like a baby (a nine-week-old, to be exact) in her cozy, blanket-lined computer box, safe and secure near my desk in the darkened laboratory. Finally, all the conditions are right: the microscopic neuron, vividly fluorescing down to its tiniest branches, an electrode carefully implanted to measure its electrical activity. I'm about to stimulate the cell's input pathway, to test whether it will "learn" from simulated sensory experience--when of course, Julia wakes up and wants to be fed.
What the heck. I pick her up, hike up my shirt, and start nursing, all the while twiddling dials with my free left hand. "Take off the holding current," I tell myself. "Set the extracellular voltage, configure the data acquisition, and then go!" The pulse goes out, the neuron fires a lovely train of electrical potentials, and the cell fills with calcium, color-coded, on the computer screen, with red for the most intense spots, yellow in between, and blue for the "cold" spots--distant branches that don't seem to have many pores for calcium to flow in. It's a great cell, an almost ideal experiment, until Julia suddenly pulls off my breast (curious, no doubt, about the flash of light on the computer screen) and, kicking her right foot into the delicate micromanipulator, knocks my perfect electrode right out of the perfect cell.
"No!" I wail, staring in disbelief at the computer screen. I watch as the neuron blows up into a big balloon, its membranes ripped open by the moving electrode. As it ruptures, the image on the computer screen flashes to red, then fades to orange, yellow, green, and blue as the dye dissipates. The cell is dead, a quick demise that is painful only for me.
Nobody ever said it would be easy being a mother and neuroscientist. But the juxtaposition does have its rewards at times. Here I am, trying to figure out how the neurons in a young rat's brain change with experience, and I have my own little experiment brewing right under my nose. Annoyed as I am by Julia's gymnastics, who can blame her baby brain, just trying to get some exercise for its budding motor pathways? Everything I'm trying to study in young rats is going on in her small head, a billion times over, every second of every day.
I spent ten years studying neural plasticity--the ways our brains change with experience--before Julia came along. I always knew I wanted to have children, but I had no idea how much my own research related to parenting until I actually became a mother myself. Like most new parents, I found myself suddenly fascinated by the nature/nurture issue, the degree to which Julia's future talents and weaknesses would be a product of our genes or her experience. The question is as old as humanity itself, but it is more than a mere academic debate. Whether one sides with "nature" or "nurture" makes a tremendous difference in the way we, both as parents and a society, raise our children.
Earlier in this century, the pendulum had swung fully to the "environmental" side. In a famous series of studies in the 1940s, psychiatrist Rene Spitz compared two groups of disadvantaged babies: one group was raised in what was then considered a perfectly adequate foundling home, and another group was comprised of infants whose mothers were in prison and who were being reared in a nearby nursery. Although both institutions were superficially similar--both were clean and provided the babies with adequate food, clothing, and medical care--they differed enormously in the amount of nurturing and stimulation each provided.
Babies in the prison nursery were fed, nursed, and cared for by their own mothers, who lavished enormous attention and affection on them. These children developed normally, in spite of the institutional setting and the fact that the number of hours of contact with their mothers was limited. Babies in the foundling home, by contrast, had very little stimulation; there was only one nurse for every eight infants, and except for brief feedings and diaper changes, each baby was kept isolated in his or her crib, its sides draped with sheets to prevent the spread of infection. With nothing to look at or play with and, worst of all, a bare minimum of human contact and affection, these babies suffered devastatingly. An enormous number didn't even survive to two years of age. Those who did were physically stunted, highly prone to infection, and severely retarded, both cognitively and emotionally. By three years of age, most couldn't even walk or talk, and in marked contrast to the exuberant nursery-reared children, they were strikingly withdrawn and apathetic.
Spitz's work went a long way toward changing adoption policies--eliminating the waiting periods that were at one time thought necessary to allow babies' "natural" personalities and intellectual talents to unfold. Early adoption is now universally recognized as the best option for orphans and unwanted babies, although the tragic fact is that babies in many parts of the world continue to wither in orphanages even worse than Spitz described.
Spitz showed that early nurturing and stimulation are essential to child development, and he was not alone in this view. At the time, the field of psychology was dominated by the theory of "behaviorism," which proposed that all our actions, from the simplest smile to the most sophisticated chess move, are learned through reward and punishment, trial-and-error interactions with other people and objects in the world. Babies, according to this view, are born as "blank slates," without predispositions, and infinitely malleable through parental feedback and tutoring. John Watson, the founder of modern behaviorism, even went so far as to claim:
Give me a dozen healthy infants, well-formed, and my own specified world to bring them up in and I'll guarantee to take any one at random and train him to become any kind of specialist I might select--doctor, lawyer, artist, merchant-chief, and yes even beggar-man and thief, regardless of his talents, penchants, abilities, vocations, and race of his ancestors.
No doubt Watson overstated his case, but such emphasis on early environment eventually led to the establishment of important social programs like the welfare safety net and Head Start. If children are so greatly malleable, then the best way to ensure a great society is by improving the environment of its youngest members.
These days, things have swung to the opposite extreme. We are now fully entrenched in the Era of the Gene. Every day, molecular biologists get a little closer to pinpointing which stretch of chromosome is responsible for some dreaded disease or complex behavior--alcoholism, Alzheimer's disease, breast cancer, dyslexia, sexual orientation. The government-sponsored Human Genome Project has made us heady with the potential of "decoding" the blueprint for every individual, figuring out where each of our strengths and weaknesses lies, what troubles may lie ahead, and eventually, how to cure our genetic ills. These fast-paced discoveries are exciting, to be sure, but the renewed emphasis on genes also has its discomfiting side--the tendency, fostered by books such as The Bell Curve and The Nurture Assumption, to say that parents and society make little difference. A child's fate, according to this view, is largely determined by heredity, leaving little we can do to improve matters.
As a neuroscientist, it's hard to fully accept this position. Of course, genes are important, but anyone who has ever studied nerve cells can tell you how remarkably plastic they are. The brain itself is literally molded by experience: every sight, sound, and thought leaves an imprint on specific neural circuits, modifying the way future sights, sounds, and thoughts will be registered. Brain hardware is not fixed, but living, dynamic tissue that is constantly updating itself to meet the sensory, motor, emotional, and intellectual demands at hand.
My own fascination with neural plasticity was only magnified with newborn Julia in my arms. If ever there was a time for experience to mold her brain, this was it. Although we know from studies of adult learning that the brain remains malleable throughout life, it is massively more so in infancy. Brain surgeons can even remove an entire hemisphere from the cerebral cortex of a young child (which in rare instances is the only treatment for profound epilepsy), and he or she will suffer surprisingly little loss of physical function or intellectual capacity.
I found myself wondering about every interaction: What is this caress, this diaper change, this lullaby doing to Julia's brain? Which circuits are already turned on, and which are still wiring up? What happened, at six weeks, to make her suddenly start smiling, or at eighteen weeks, so that she could finally reach out and grasp her rattle? Can Julia see those computer designs I taped up in her box? Hear the neuron firing away through the audio monitor? Know that I am her mother? Are we, her enraptured parents, in any way responsible for these wiring events, or would they have happened without any particular nurturing on our part, unfolding, like a budding flower, along a programmed trajectory that requires nothing but the most basic food, water, and air?
In other words, I needed to know: What is going on inside that little head, and what difference can I, as a parent, make in her putting it all together?
Product details
- Publisher : Bantam
- Publication date : October 3, 2000
- Edition : 1st
- Language : English
- Print length : 544 pages
- ISBN-10 : 0553378252
- ISBN-13 : 978-0553378252
- Item Weight : 1.45 pounds
- Dimensions : 6.12 x 1.34 x 9.15 inches
- Best Sellers Rank: #49,257 in Books (See Top 100 in Books)
- #49 in Medical Child Psychology
- #100 in Popular Child Psychology
- #122 in Baby & Toddler Parenting
- Customer Reviews:
About the author

Lise Eliot, a graduate of Harvard, received her Ph.D. from Columbia University. She is Associate Professor of Neuroscience at The Chicago Medical School of Rosalind Franklin University of Medicine and Science. The mother of two sons and a daughter, she is also the author of What's Going on in There? How the Brain and Mind Develop in the First Five Years of Life.
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- Reviewed in the United States on October 10, 2012"What's Going on in There? How the Brain and Mind Develop in the First Five Years of Life" is titled accurately in that it discusses in much detail the processes that are going on in the brain through a child's 5th year. The book is organized in 17 chapters covering topics from how the visual system develops to how intelligence and memory is processed in the younger ages. What is great about this book is that statements are fully backed up by previous research which makes the book a reliable source for those wanting to learn how to raise a child. But it is also useful for those merely interested in the development of the brain. Overall, "What's Going on in There?" provides a great depth of knowledge; however the details sometimes detract from those simply wanting advice on how to rear a child.
Critique/How to Read the Book
Because of the dense material covered in Eliot's book , it is difficult to turn to a page you want to learn about at random. Also, the lay out of the book being that it is organized into chapters on topics rather than in chapters by chronological age makes it challenging to turn to the sections for a 3 year old if let's say you just bought the book when your child was 3-4 years old. To overcome these, I suggest that if you are reading this book as a resourceful guide on what to expect and how to raise your infant, it is best to read this ahead of time and highlight the parts you think are important. In this way, you can easily refer back to the sections you thought were helpful. Additionally, it is important to note that the chapters are mostly organized in chronological order from the fetus stage, early infant, then on to its toddler and pre-school years. Therefore, you can skim through the end of a chapter in an area of interest if you already have a child who is in his/her toddler years.
First Few Chapters
The first few chapters focus on the basics of the brain in an evolutionary and anatomical sense. It discusses the egg's fertilization, passage through the fallopian tube, and implantation in the uterus, as well as briefly discusses the cellular growth in the cerebral cortex, "increasingly spiky or complex" EEGs, and of course the argument of nature versus nurture.
Prenatal Influences
An entire 55 pages are devoted to explaining the "Prenatal Influences on the Brain." A section of this discusses how the nicotine and carbon monoxide found in cigarettes adversely affects the fetus. They "decrease the amount of oxygen available to the fetus, and less oxygen means slower growth of all bodily organs." The effects of maternal stress are fully explained by first providing in depth information on the how the fight-or-flight response works. There is even a table at the end of the chapter summarizing the prenatal factors (toxins, radiation, other chemicals, etc.) that are harmful, non-conclusive, and recommendations for how to avoid the harmful factors.
Importance of Being Held
One of the most well explained and interesting parts of the book are the chapters, "The Importance of Touch" and "Why Babies Love to Be Bounced." Eliot describes how the vestibular system develops from a fetus to an infant using plenty of pictures and diagrams first, which then helps her describe specific studies on how cuddling and holding a baby lead to a behavior that is less irritable as children. There are many benefits to vestibular stimulation at a young age including "newborns cry less when they are being rocked, carried, jiggled, or suddenly changed in position, all actions that activate the vestibular system;" overall behavioral state in "decreasing the baby's level of arousal;" and pre-term babies being "less irritable, move less jerkily, and sleep more."
Senses
Even if you are only interested in how the visual, gustatory, vestibular, and auditory systems work in humans, you will receive an abundant amount of information regarding these systems because the chapters first discuss the basics of how each develops, works together, and the components involved in each. Eliot does an excellent job in describing the beauty of each part while providing useful information on topics such as how hearing improves (in terms of frequency sensitivity, sound localization, threshold and the ability to discriminate sounds in a noisy background), obligatory looking (where babies fixate on an object for minutes at a time), binocularity and depth perception, and the function of prenatal taste ability.
Debunking Myths
What makes this book even more interesting is that it covers many of the myths or statements you hear people making regularly. Eliot explains how being exposed to a variety of tastes at a young age influences later preferences making the adults more likely to try and also like non-novel foods. She shows that acquired taste has a large role in this process rather than genes. "What's Going on in There?" also explains how infant walkers don't really help infants walk mainly because of its limiting effect on an infant's ability to explore the world on its own, stimulating various parts of his/her brain. She states, "They can explore and satisfy their curiosity without developing their balance or locomotor skills, so these abilities come more slowly."
Smarter Child?
The last few chapters provide the most information in terms of practical use that parents can utilize to encourage a better lifestyle, memory, and social emotional growth. Even though Eliot describes countless ways of improving these based on previous research conducted, she states an important view to keep in mind. "It is the model we set, rather than the specific teaching we attempt, that is going to have the biggest impact on a child's cognitive abilities and success in life."
Conclusion
In conclusion "What's Going in There?" by Lise Eliot, provides wonderful explanations as to how the brain develops from a fetus through age 5. It provides a myriad of useful information and debunks I would greatly recommend this book to one simply wanting to learn more about the details of how the brain is formed and how much plasticity there is at an early age. I would also recommend this great book to mothers-to-be or one who already have an infant to use as a resource to refer to. It is detailed enough to not only know what is going on in the brain, but also understand the processes taking place! What you do with these facts from diagrams or previous studies is up to you though since Eliot focuses more on the actual material rather than how to implement this knowledge into practical use- which may be a challenge if you do not have a very good science background but can be great for those who already know some in this area to form your own ideas.
- Reviewed in the United States on May 20, 2004This book is for the parent who wants to know all the "Whys." I have identical twins, so it is very interesting to me to see why their personalities might be different. Identical twins are used in many experiments, so I found this book especially interesting. My mother-in-law is also a pschologist and did many "experiements" with my husband (wish they had video cameras back then -- would have been neat to see). :) My husband and I have always been fascinated with child development since our children were born. This answered all our questions!
It is a very technical, detailed book, but it is not too far over an average parent's head to get something out of it. I did find myself skipping over some of the parts that got bogged down in details (I just want to get to the point sometimes), but I would get the main idea. My husband and I found this book while searching for a more scientific book on brain development. We were watching a series on TLC that showed different experiements done with children and when children acquire specific skills and why. We tried finding it again without success, so we searched for a book instead. You can find tons of books that tell you when your child should do what, but they don't tell why and what is really going on in their heads. This book will explain all that!! You will even learn things like why toddlers should drink whole milk until the age of 2! It is broken up into the different senses as well as being chronological, which I found really easy to follow.
This will definitely make you a better parent. As an educator myself, I find it fascinating just to have the knowledge, and I feel it is important for all parents to have this knowledge. You will learn how to stimulate your child at different ages so that his/her brain develops to its fullest. You and your child will be happier and more relaxed just having the information contained in this book.
The only regret I have is not having read it sooner! I had all the other parenting books, but I never felt fulfilled reading them. I didn't want a list of milestones, I wanted to know why they do milestones when they do. This is the only parenting book you need! I recommend reading it before your children are born, but it is never too late to read it! Mine were 2 when I got this book!
- Reviewed in the United States on July 12, 2007For some reason, I thought this book would be more about what my baby is thinking. Instead it is very much about biology. Every chapter starts with a discussion of when a certain part of your baby's brain began developing including regions, names, and discussions about when and how fast the nuerons in that area mylenate. This leads to discussions about what your baby's brain can and cannot do and when that changes. You can extrapolate from this information to get an idea of "Whats going on in there?", but it isn't really what the book is about. For example, the book discusses that your baby can smell right at birth (maybe before) and that the scent of the mother and milk and so on play a roll in bonding. Then, it talks about the tests that were done to show that this is true. It never says whether or not your baby would enjoy more smells, or maybe which smells, or even if it matters whether or not there are any smells. For me, I wanted that kind of information, not so much biology. For example, if her room seems a bit stuffy to me, will is seem that way to her? Should I delay her nap time by 5 minutes to maybe open the windows and air it out, or could she care less? This book does not answer those kinds of questions.
However, as a baby brain biology book, I have no doubt that this is probably the tops on that score. It is interesting to know how your baby's senses develop and what her brain is and isn't capable of at a certain age. So if you want a book about that, this book is great, it is easily readable, and very accessable (the brain has complicated names for its parts, but there is nothing the author can do about that). If you are looking for a book that lets you in on what might be going on in that little head of hers...well, I haven't found that book yet.
Top reviews from other countries
SrikanthReviewed in Germany on May 6, 20175.0 out of 5 stars A must read for every parent
I enjoyed reading this book. A must read for every parent who wants to provide the best care for their child (and who doesn't?). This book has a lot of scientific information as well for those interested in those topics, but it doesn't mean that this book is a scientific read. It has a perfect blend of both scientific and "general" topics, probably a little more on the non-scientific side, which makes it even more interesting (at least for me) and doesn't make it feel like you are reading a technical book. You will understand a great deal on how brain works, not just in children, but also in adults.
I especially enjoyed reading the last few chapters of this book (Chapter 12 to 17) which provide a lot of practical information on how raise a "smarter" child.
MayaReviewed in the United Kingdom on April 18, 20205.0 out of 5 stars Useful, in depth, yet enjoyable
I am expecting my first child and this book was very useful preparation for me. It explains in accessible scientific details how a child develops from conception to early childhood and what is the parents and environment role in this.
Knowing this information helped me and my partner decide what to do with all the advice we are getting as first-time parents and feel more confident. It is also a very enjoyable read.
M. VanReviewed in Spain on November 11, 20185.0 out of 5 stars A must-buy in my opinion!
I am now expecting my second child and rereading this book. It has helped me so much with my first one! It does really help you understand well what is going on in there (as the book says) from a scientific point of view (aren't you tired of the thousands of books that are just some parents' opinions without any actual science behind their words?). And that deep understanding and knowledge can really help you maximize your child's intelligence and sociability.
By far this is the best book on this topic and a must-buy for any expectant family.
LindsayReviewed in Canada on August 25, 20105.0 out of 5 stars Excellent book
This is a great resource for parents (and parents-to-be) wanting to understand the development of a baby's brain and how it affects behaviour, physical development, first movements, nature vs nurture, personality, etc. Lots of facts and information. I found it particularly helpful when my first child was about a month old as it helped me better understand what she might be thinking or why she was behaving a certain way due to the physical changes she was going through. The book is written in a much more objective way than other books I have read and I liked that it would present the information, sometimes from various points of view, and allow the reader to make their own conclusions. I wished I had gotten this book while I still pregnant! As a new mother, I found the number of books on child development overwhelming and with the number of different "methods" being touted, I eventually decided that I was just going to read this book to try to get a better understanding on what is going on in my baby's brain as a guide and then do the best that I can with that knowledge. Great book!
ArunReviewed in India on April 30, 20195.0 out of 5 stars Must read for a science minded parent
The book goes into significant detail about the development through time for every skill. It gives a good summary of the existing body of knowledge about each skill, and suggests the course a parent should take based on the evidence we have. It is admirable that the book is so readable in spite of the detail it goes into.








