I think the Galaxy Note 10.1 is probably better known for designing and drawing with its note format and S pen stylus. The Note has a more powerful CPU with a 1.4 Ghz Quad-Core Processor compared to a 1.0 Ghz Dual Processor. It has better cameras (more megapixels). You can also purchase the Note with more internal memory than 16 GB if you want to pay extra. A notable difference is in the price: $299 versus $449 right now on Amazon. You might also want to go to Samsung.com and compare the two models next to each other.