I have osteoarthritis in my right knee and I will eventually require surgery (bone on bone). My knee is often sore, stiff and painful. I was taking straight Turmeric to help with my joints and a holistic practitioner/friend encouraged me to try Turmeric with pepper because of the better absorption. I have been taking this for a month and my knee has improved 100%. The stiffness is minimal and the pain gets dicey with a lot of walking about at work but I have not had to take my Ibuprofen 800mg in about 2 weeks now. Give it a try. It has really made a difference in how I feel. Love it.