Oh my- this is a fantastic book. It is a quick read because it is so fascinating. I've followed Holmes since she was on the cover of magazines wondering just what she was doing. I've worked on an IRB committee (research ethics),and the entire time I was reading this book I was shocked at the lack of ethics on the parts of almost everyone in the story. They KNEW they were going to use this machine; they knew it wasn't ready; they knew Holmes was lying and deceiving and then ritually firing people who found her out, but not ONE person went to the FDA or even the SEC or FBI or whomever to say it was a fraud? And it was quite a fraud. One that was using human beings in its testing. The writing is compelling, and the story is so unreal that you can hardly believe it is true. Somehow it seems to boil down to greed. If this were fiction, you'd laugh in spots at how preposterous it seems. But it isn't fiction. It is a terrible saga of deception and manipulation, and it proves that when money is involved, people see what they want to see and hear what they want to hear.