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Jarrow Formulas Pantethine 450 mg - Derivative of Vitamin B5 - 60 Servings (Softgels) - Support Heart Health, Carbohydrate & Lipid Metabolism - Coenzyme A (CoA) Precursor - Pantothenic Acid Supplement

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4.2 825 ratings

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Brand	Jarrow Formulas
Flavor	Unflavored
Primary Supplement Type	Vitamin-b
Unit Count	60 Count
Item Form	Softgel
Item Weight	0.07 Kilograms
Item dimensions L x W x H	6 x 5 x 4 inches
Special Ingredients	Pantethine
Diet Type	Gluten Free
Product Benefits	Heart Health Support

About this item

B5 Vitamins: Pantethine supports and supplies a derivative of vitamin B5 to support normal healhty lipid metabolism*
Pantothene Supplements: Each softgel provides 450 mg of pantethine for supporting cardiovascular and normal healthy lipid metabolism*
Pantethine Supplement Benefits: Jarrow Formulas Pantethine supports carbohydrate and lipid metabolism, as well as heart and cardiovascular health*
Pantethine Softgels: Panthethine is non-GMO, soy free, gluten free, dairy free, egg free, fish/shellfish free, peanuts/tree nuts free, and sesame free
Suggested Use for Vitamin B5 Pantothenic Acid: Adults take 1 softgel per day with a meal or as directed by your qualified healthcare professional

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From the manufacturer


Our formulations are carefully crafted and informed by strong scientific research. We are 100% dedicated to getting every formula right.	Jarrow Formulas heart supplements provide a wide range of nutrients, antioxidants, and botanicals that support healthy blood circulation and heart health.*	We evaluate ingredient purity and only work with suppliers who follow Current Good Manufacturing Practices (cGMP) for our capsules, tablets, softgels and powder formulations.


	Max Absorption QH-absorb	Red Yeast Rice	Cardiovascular Optimizer	Pantethine	Citrus Bergamot
	Buying Options	Buying Options	Buying Options	Buying Options	Buying Options
Customer Reviews	1,944	1,637	1	825	1,902
Primary Benefit	Supports Mitochodrial Health, Cellular Energy Production & Healthy Cardiovascular Function*	Supports Cardiovascular Health*	Supports Cardiovascular Health*	Supports Normal Carbohydrate & Lipid Metabolism*	Supports Metabolic Health*
Key Ingredients	Kaneka Ubiquinol	Red Yeast Rice, Coenzyme Q10	Red Yeast Rice, Proprietary Mushroom Blend, Hawthorn Extract	Pantesin Pantethine	Citrus Bergamot Extract
No Major Allergens	✓	✓	✓	✓	✓
Form Type	Softgel	Veggie Capsule	Veggie Capsule	Softgel	Veggie Capsule
Size Options	30, 60 & 90	120	120	60	60 & 120

Product Description

Jarrow Formulas Pantethine is a derivative of vitamin B5. Pantethine supports lipid metabolism through its ability to raise levels of CoA, a cofactor involved in several metabolic pathways, including carbohydrate and lipid metabolism.* Each serving of Jarrow Formulas Pantethine softgel provides 450 mg of pantethine for supporting normal healthy lipid metabolism and heart health .* This formula provides the derivative form of vitamin B5. Anyone looking for vitamin B5 to support normal healthy lipid metabolism and heart health will find these products useful.* Panthethine is non-GMO, wheat free, soy free, gluten free, dairy free, egg free, fish/shellfish free, peanuts/tree nuts free, and sesame free. Suggested use: Adults take 1 softgel per day with a meal or as directed by your qualified healthcare professional. At Jarrow Formulas, we aren't your typical vitamin company. We believe everyone has the right to feel good in their own body. Superior science. Smarter formulas. Jarrow Formulas original goal has always remained the same: To design superior dietary supplements that help empower individuals to take charge of their own health.*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Product details

Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 6 x 5 x 4 inches; 2.47 ounces
Item model number ‏ : ‎ PANT
Department ‏ : ‎ unisex adult
Date First Available ‏ : ‎ October 2, 2001
Manufacturer ‏ : ‎ Jarrow Formulas
ASIN ‏ : ‎ B0013OXA4K

Best Sellers Rank: #27,241 in Health & Household (See Top 100 in Health & Household)
- #5 in Vitamin B5 (Pantothenic Acid) Supplements
- #2,243 in Diet & Sports Nutrition
- #2,317 in Sales & Deals

Customer Reviews:
4.2 825 ratings

Important information

Safety Information

This product is labelled to United States standards and may differ from similar products sold elsewhere in its ingredients, labeling and allergen warnings

Indications

Supports Lipid Metabolism*

Ingredients

Pantethine, Other Ingredients: Softgel (bovine gelatin, glycerin, purified water, annatto [as a light barrier]).

Directions

Take 1 softgel per day with a meal or as directed by your qualified healthcare professional.

Legal Disclaimer

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer reviews

825 global ratings

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Customers say

Customers like the quality and value of the nutritional supplement. They mention it helps reduce cholesterol and triglyceride levels. Some are also happy with the sleep quality. However, some customers have reported that the capsules were melted together and the gel caps were all stuck together. They also say they have diarrhea and disagree on its functionality.

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Cholesterol reduction Quality Value for money Sleep quality Functionality Melted capsules Sturdiness Diarrhea

56 customers mention "Cholesterol reduction"56 positive0 negative

Customers find the product helps reduce cholesterol. They mention it helps drastically reduce their cholesterol and triglyceride levels within 2 weeks. Some say it provides some modest benefits.

"...I have not had any allergic reactions to it. Also don't get any bad taste from it or any 'kick back' from whatever oil is within it...." Read more

"...In both forms (pantethine and pantothenic acid) it's good for the heart, brain and adrenals...." Read more

"...LDL 192 LDL 173This supplement did a great job lowering my triglycerides and my VLDL but did not lower my other numbers enough to..." Read more

"...LDL is down from 194 to 149. My triglycerides are about the same and my HDL went up." Read more

34 customers mention "Quality"31 positive3 negative

Customers are satisfied with the quality of the product. They mention it's a great product and easy to swallow.

"This product delivers the best quality and easiest to swallow pantetheine I have used...." Read more

"...Good price and quality was fine. I tried buying twice in August and both times the capsules were melted and/or liquified in the bottle...." Read more

"Great product" Read more

"Good product." Read more

12 customers mention "Value for money"12 positive0 negative

Customers appreciate the value of the product. They say it's a good product at a good price.

"Prior to August 2024, I had bought this item several times. Good price and quality was fine...." Read more

"Good price. Also has helped lower my cholesterol as part of my program" Read more

"Exactly what I expected. Great price. I’ve been using this and feel like it was helping...." Read more

"Best price/volume pantethine (I did the math). Just take one of these whenever you eat a fatty meal and the 1-3 zits I get never appear. Bingo bango." Read more

9 customers mention "Sleep quality"9 positive0 negative

Customers are satisfied with the sleep quality of the product. They mention it's great for adrenal fatigue and stops angina. Some say it makes them feel more energetic and awake all day.

"...I still wake up, but I fall asleep pretty easily. I would highly recommend this product if you have high cholesterol because of bad genes." Read more

"Worked great for me. Lower BP and Cholesterol. Also, stopped Angina. Take one per day." Read more

"...This product relieved the itching. Ct" Read more

"i like this product, which really help my adrenal fatigue problem. i recommend anyone with adrenal fatigue try it with PABA." Read more

22 customers mention "Functionality"12 positive10 negative

Customers have mixed opinions about the functionality of the product. Some mention it works great and has no issues, while others say it's unusable and a waste of money.

"...I have a deficiency in B5 and this product works the best to correct it...." Read more

"...My fourth bottle purchased from Amazon is unusable. Like many products from Amazon, it was obviously not stored correctly...." Read more

"...Tryglicerides from 90 to 83This product actually works...." Read more

"...There are no refunds or exchanges!!! This is not a cheap product...." Read more

15 customers mention "Melted capsules"0 positive15 negative

Customers are dissatisfied with the melted capsules of the nutritional supplement. They mention that the caps had disintegrated and melted together. Some say the bottles had been overheated so much that the capsules had melted.

"...My bottle arrived and every single capsule is melted together at the bottom of the bottle in one huge clump!! There are no refunds or exchanges!!!..." Read more

"Came melted as a lump...." Read more

"...my front door and retrieved promptly had been heated and all the capsules melted together...." Read more

"...& Save from shipment on September 19th and all the softgels are melded together on the side of the inside of bottle...." Read more

12 customers mention "Sturdiness"0 positive12 negative

Customers are dissatisfied with the sturdiness of the product. They mention the gel caps are all stuck together and hardened.

"...The gel caps are all stuck together and hardened. Some of the gel caps had obviously broken...." Read more

"...weekly pill box and the pantethine capsules were very sticky and clumped together. They even left a sticky residue on my fingers...." Read more

"...The second bottle was all stuck together in a lump and unusable. Amazon would not allow a return, directed me to Jarrow for support...." Read more

"...All pills stuck together. Company need to check their supply. Clearly something went wrong with the whole batch...." Read more

7 customers mention "Diarrhea"0 positive7 negative

Customers are dissatisfied with the diarrhea that the product causes. They mention it gives them gastritis, persistent diarrhea, and makes them violently sick. Some say the product causes chest pain immediately and develops muscle pains in their legs.

"...s in this, or if i just may be extra sensitive to it, but this made me so sick. A week or so ago, i thought i had caught a stomach bug...." Read more

"I stopped taking this because it gave me a low-grade headache...." Read more

"...(2 moths after my initial review, I developed muscle pains in my legs...." Read more

"...Unfortunately they gave me persistent diarrhea so I wasn't able to put them to the test." Read more

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Memento Mori

Pantethine is great for lowering cholesterol

Reviewed in the United States on June 3, 2009

Verified Purchase

Pantethine is an active form of vitamin B5 that has been shown to lower cholesterol more than cholesterol lowering medications without ANY significant side-effects.

"In multiple clinical trials of patients with elevated cholesterol and triglycerides, total and LDL cholesterol were decreased by 12%, triglycerides decreased by 18%, and HDL cholesterol was increased by 9%. These clinical trials were conducted with daily intakes ranging from 600 to 1200 mg/day. Within this dose range there is no evidence of a dose-effect relationship, i.e. changes in lipid concentrations overlapped across the range of doses. Direct dose-response evidence is not available because no trial tested more than one dose. A few trials tested 300 mg/day with more modest but still statistically significant results."

The above quote is from the Wikipedia article on Pantethine, these are the sources:
Binaghi, P; Cellina, G; Lo Cicero, G; Bruschi, F; Porcaro, E; Penotti, M (1990). "Evaluation of the cholesterol-lowering effectiveness of pantethine in women in perimenopausal age". Minerva medica 81 (6): 475-9. PMID 2359503.

Arsenio, L; Bodria, P; Magnati, G; Strata, A; Trovato, R (1986). "Effectiveness of long-term treatment with pantethine in patients with dyslipidemia". Clinical therapeutics 8 (5): 537-45. PMID 3094958.

Gaddi, A; Descovich, GC; Noseda, G; Fragiacomo, C; Colombo, L; Craveri, A; Montanari, G; Sirtori, CR (1984). "Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia". Atherosclerosis 50 (1): 73-83. doi:10.1016/0021-9150(84)90009-1. PMID 6365107.

48 people found this helpful

Helpful

Amazon Customer

Best quality

Reviewed in the United States on May 21, 2024

Verified Purchase

This product delivers the best quality and easiest to swallow pantetheine I have used. I have a deficiency in B5 and this product works the best to correct it. It is one of the only supplements that I have purchased repeatedly and I am never without it.

3 people found this helpful

Helpful

Diane Williams

Total Cholesterol was 413

Reviewed in the United States on April 26, 2022

Verified Purchase

Most people never heard of someone with total cholesterol over 400. It’s 100% genetic in my family. My mother is 480, my father was 380, my sister is 410, etc. None of us take statins. My mother is 92 and has no heart issues. My father never had heart issues and passed away at 96 from falling.

A common reaction is that I’m probably obese, I eat junk, and/or I don’t exercise.

At age 63, I’m not obese or overweight. I’m 5’0” and weigh 97 pounds.

My meals have been the same for many years. Green tea and a half bagel with some cream cheese for breakfast. A green smoothie (cranberry juice, lemon peel, strawberries, blueberries, banana, apple, spinach, kale, and collagen powder), dried cranberries, nuts, and one cookie or small chocolate for lunch. A salad, fruit, cooked vegetable, and small portion of the main meal for dinner. I limit myself to eating out (junk food) two times a month. My vice is a half scoop of ice cream at night.

I’m a workout fanatic and taught bootcamp classes at the gym before Covid broke out. Last year, I did 376 workouts. I live at 7,000 elevation. My workouts are very rigorous for a 63 year old female. As people ski downhill, I’m the only one skate skiing uphill. I don’t use chair lifts. I mountain bike uphill to the summit at 8,500 feet. I do 5K races and usually finish in the top 3 at 7,000 elevation for my age group 60-69.

Being so physically active, I hated statins. It bothered my muscles and joints and affected my workouts. I discovered Pantethine is for people like me who genetically have high cholesterol and can’t lower their cholesterol through diet and exercise. I took 1 Pantethine capsule per day with my dinner for 4 months as an experiment and had my bloodwork redone. The results are:

Total Cholesterol from 413 to 325
HDL from 66 to 66
LDL from 329 to 242
Tryglicerides from 90 to 83

This product actually works. There’s no way I could have dropped my total cholesterol from 413 to 325 without it. There was only 1 side effect. My sleep is much better now. About 2 times a week, I woke up and tossed and turned in bed for 2-3 hours. After taking Pantethine, that only happened 2 times in 4 months. I still wake up, but I fall asleep pretty easily. I would highly recommend this product if you have high cholesterol because of bad genes.

166 people found this helpful

Helpful

Lovely

Projectile vomiting

Reviewed in the United States on September 18, 2023

Verified Purchase

Idk whats in this, or if i just may be extra sensitive to it, but this made me so sick. A week or so ago, i thought i had caught a stomach bug. I was vomiting and had (TMI) waterfall diarrhea for 4 straight days. All of this started as soon as i added this to my vitamin regime, but i never thought a supplement could make me so sick. I’ve never in my life ever had any such reaction to any supplement. Maybe mild discomfort, but never as bad as this was. I ended up having to go to the ER because i couldn’t keep anything down not even pepto, and i was so dehydrated that my body was weak and in so much pain. I ate nothing for like 4 days and lost like 10lbs! I stopped taking this along with all my other vitamins because i would literally just vomit it all up as soon as i swallowed them. They gave me pain medication and anti vomiting meds + saline to hydrate me at the hospital. And they told me that i tested negative for bacterial and viral infection. I was so confused. Then why is my stomach in so much pain?!. I came back home and slowly started re-introducing food as well as my vitamins. I started with the vitamins I was most familiar with. The ones that I’ve taken for months with no problem. Well yesterday i added this back into the mix and what’ll you know, projectile vomiting and waterfall diarrhea 2hrs later. I vomited about 5 times yesterday and can’t even count the amount of times it came out the other end. At one point i chucked this in the garbage and glared at it as it got coated in my 5th vomit round (at this point it was just bile). This made me violently sick. I was so in so much pain, and so weak after being sick for hours that it was hard to even fall asleep. Lucky i still had some of the meds they prescribed me at the hospital last week. The only thing that stopped the sickness was prayer and OD-ing on the dissolvable pepto (i just let it sit in my mouth and slowly dissolve, every time i tried to chew and swallow =🤮). Once i broke the cycle i could take the meds from the hospital with the tiniest sip of water. Yea idk what’s in this but my body hates it.

5 people found this helpful

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Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.

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Jarrow Formulas Pantethine 450 mg - Derivative of Vitamin B5 - 60 Servings (Softgels) - Support Heart Health, Carbohydrate & Lipid Metabolism - Coenzyme A (CoA) Precursor - Pantothenic Acid Supplement

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Critical Supplement for Adrenal Health

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I bought 2 bottles of 60 caps but there are only 28 capsules