This book takes a look at the extremely complex human genetic pathways system and makes it as simple as is humanly possible to understand, which is not easy. I've had to review parts of it several times to try to grasp the science involved. The great thing about this book is that it gives me hope after 10 years of misery, without have to completely understand the science. It gave me an action plan with supplements that one can buy here on Amazon or off the shelf. It provides one with a cautionary plan to move forward with to see if a difference in your well being can finally be had. I literally have a huge box of supplements that I either bought, hoping that they would provide relief, or useless supplements that a doctor recommended, and did nothing. I've seen 10 different specialist here in Anchorage, AK and went to the Mayo clinic as well. The only thing that has helped me is discovery of a B12 deficiency that I now know can only be alleviated thru injections once a week. Better that than total misery all the time. But, I have since discovered that that is only one of the methylation issues to be addressed. I have other problems that 23 and me and stratgene have helped to identify, but one really needs this book, or one like it, to navigate, otherwise that information is useless. Buy the book. It is changing my life for the better as I sit and write this review. There is no magic elixir that is going to cure me. But the knowledge gleaned from this book will help me get there. This book is really a Godsend. Thanks Doc!