The Southern Reach trilogy is a pretty crazy work. For large portions of these books it can be "you don't know what's going on but for it to be interesting enough that you enjoy it despite that fact". This is where VanderMeer excels. His portrayal of the events keeps you invested in the characters and story despite its unclear nature. Book two was my favorite of the three, as it ties just enough together that even though you don't have all the information the story feels cohesive.
All that said I was not completely satisfied with the ending. A few too many characters get introduced and not explained. Again with a series like this I don't expect to know all the information, but I need to know just enough. So while certainly not a bad ending, given his structure and the setup we get from book two, I was expecting a more complete tie up and for me I don't think that was achieved.
Overall I got a lot of enjoyment out of this series and the unique style and story telling alone justified the read. So yeah give it a shot if you're interested.