We use these for a community radio station, and has used the 1st and 2nd gen 2i2s for years without problems. They fail after 2-3 years of 24x7 use, but that seems reasonable.
However, the 3rd gen switches to a USB C connector with lightning, which requires a separate driver. In order to deliver this driver, the interface shows as a USB drive with the installation media. This causes the system not to boot if the device is plugged in. Focusrite also tries to get you to register the device and drivers with their web sites before the USB connection can be made.
The new driver is also dropping connection after extended periods. Look for gen 1 or 2 of this device if you aren't using it for short periods, and unplugging it after you are done.