In 2008, the National Academy of Engineering (NAE) identified a set of grand challenges for engineering for the 21st century that when solved would provide huge benefit to the global society. As cited in chapter 11, Looking to the Future, “what is common to these challenges in that they are all complex systems problems, and they all require contributions from multiple disciplines to frame the problem correctly.” The preceding ten chapters of this seminal book identify trends, methods and real world examples from disparate domains of how transdisciplinary systems engineering thinking can be applied to help frame these complex problems and then endeavor to solve them. Particularly insightful in its elegance in correctly framing the problem is the chapter on “From Models to Stories” which showcases an illustrative example for a campus security system. The foreword of the book, which is provided by Norm Augustine, former chair of the NAE, cites the importance of the book for the examples of “cross-disciplinary approaches to solving problems that appear intractable when viewed through the lens of a single discipline.” This book is a must read for every engineer and program manager to understand current and future trends that will impact their world. The book is easy to read, yet truly expands one’s perspectives of systems engineering and solving complex problems.