This is a fantastic book that gives an inside look at the effects of antidepressant. In the book, Kirsch shares how he went from being a believer in effects of antidepressant to a doubter and finally a disbeliever. He gives all the evidence to back up his claims, showing that antidepressants are no better than placebo. He also shows that the chemical imbalance theory of depression is severly flawed. He points out that drugs that lower serotonin in the brain work just as well as those that increase serotinin. He also show that drugs such as benzodiazapines, opiates, and thyroid hormones work equally as well. This all points towards the conclusion that the placebo effect is the real reason for the improvement. When people are given a drug, they expect they will get better. This is an exeptionally written book that will keep you turning the page to uncover more evidence about the science of antidepressants. It's more than just a book about antidepressants, it's a story about how science works and why it is slow to change despite evidence to the contrary.