I've applied this type of screen protector in the past (on my iPod Touch, Nintendo DS / DSi, and my PSP). Using the tips below, I was able to apply this LCD screen protector 99% bubble free. I was actually pleasantly surprised I was able to do this since it was by far the largest screen protector I've ever applied.
The instructions that come with the package are not very helpful. Below are mine. Hope they help.
INSTRUCTIONS / TIPS ====================
1) CLEAN the surface of your iPad. Use a microfiber cloth and even use a compressed air can if you want to be sure. Position yourself or a light so that you would be able to see ANY specs. Any leftover specs will raise the screen protector and will give you a bubble that you CANNOT remove. Keep the iPad's screen OFF so you have a better chance of seeing any specks.
2) First remove the plastic envelope/pouch that directly contains the screen protector.
3) Without removing and of the backing, place the screen protector with the hole over the iPad's circle button. Now you know exactly how much leeway you will have. Also make sure that the circle is popped out of the screen protector.
4) Find something flexible and semi-rigid to push away the air bubbles. You WILL be getting air bubbles as you apply the screen protector. The trick will be to remove them as you apply the screen protector. With smaller screen protectors, I've used credit cards. But in this case, the screen is bigger. I've found that the plastic Staples cards you get in the mail (the ones that the size of postcards) are very helpful for this task. Your second choice may be a credit card or the very thin, plastic window of a cheap picture frame. Whatever you use, make sure it has a sizable straight edge and no sharp corners (You don't want to puncture the screen protector).
6) Peel away a corner of the backing (The side labeled #1). Don't peel the whole backing off. You'll need to touch the backing in order to reposition the screen protector if necessary.
7) Continue to peel the backing but keep it minimal. You want just enough so that you can position the hole over the circle button. If you don't get it the 1st time, remove from the iPad's surface as little as possible and try again. Be careful to avoid getting any dust on the iPad's screen at this time. This is why it's good to keep as much backing on as possible.
8) After you have adequately centered the hole around the circle button, begin to slowly peel the Side 1 Backing while you use your flexible card to push away any air bubbles. Push the bubbles to the EDGE of the screen protector. If there are bubbles that are difficult to get rid of and if you're certain that's it just a bubble and not caused by specks, then you can gently remove as much backing as needed from the iPad's screen and try again. TAKE YOUR TIME.
9) Hopefully you've managed to attach the screen protector with minimal bubbles. Continue to push away as many bubbles as possible.
10) Now you need to peel of Side 2 Backing. But since the screen protector is already attached to your iPad screen, you will need to be VERY careful and slow. It's possible that the quick removal of Side 2 Backing can lift the screen protector off of the iPad screen and cause air bubbles. If there are air bubbles, use the flexible card to push away any air bubbles.
That's it, you're done. Sit back and treat yourself to a new app.
CONCLUSION ========== I liked the fact that it includes 3 screen protectors. I was able to succeed with my first one but it's nice to know that there are backups.
I didn't like the minimal instructions with the package (and the Engrish spellings). This item is very cheap. If it were more expensive, I would expect to get a flexible plastic card for getting rid of the air bubbles.
The screen protector itself has a slightly oily residue. When your iPad is off, you can see it. The residue is not visible when the iPad is turned on.