Change of life does not always mean hormonal changes. After life threatening illnesses which are now considered chronic, I broused Amazon and have purchased many books which spoke of the nature of illness and the changes which occur during their life in your body. The books spoke little of the soul. They spoke little of being dependent on others, feeling awful most of the time, asking questions of the gods which went unanswered and so on and so on. Very boring stuff. Then this book. Rachel Naomi Remen: you have answered my questions. You have polished my soul. You have taught me the lessons which meditation could not, soothed me when food could not, enlivened me when wine could not. Sitting in my doctor's waiting room, crying just reading your introduction to your Grandfather, I was called into the examining room and while having a PAP smear, read a portion of your book to my internist. I am blessed with a doctor who not only is a fine diagnostician, but a man of great humor. He said this was a first for him. Me, too. There is no time in life when reading a chapter of that book is not in perfect accordance with the rules of medicine, both physical and emotional. Thank you does not say it. I thought I was beyond words. Obviously, not. I recommend this book to everyone, sick or well....but especially to those for whom illness is a constant companion. There are many road to healing. I read somewhere: "My illness is a friend who brings me great truths." It brought me your book as well. I bless you.