I give this book a low rating not because anything in it is bad per se, only that there is nothing all that great in it either. It is broken into three sections. The first two basically discuss their theory of disease along with anecdotes from their practice. While all of this is certainly interesting you're probably reading this book for its practical application to your life. So a story about someone's drug interaction and how the doctor's diagnosed it isn't particularly relevant unless you happen to have the same weird biochemistry that that patient had. The third section contains the practical applications of everything they've talked about up to this point and this is where the disappointment sets in. I have two complaints: One, in the previous two sections they mentioned numerous medical tests (e.g. checking homocystein levels or measuring metabolic performance) as being useful for diagnosing your overall health. Yet in this section there is no mention of these tests. Which ones should I ask my doctor to perform? How often should I have them performed? Two, and this is the killer, nothing they have to say is new or different. Almost the same exact advice regarding diet and exercise is contained in my 10 year old copy of a book by the guy who did Abs of Steel. If you haven't paid *ANY* attention to health and diet literature over the past decade then what they have to say might be new to you and so the book is useful for that. But at this point you can pick up most diet and nutrition books that aren't focused on a single fad diet and they'll contain the same advice: exercise (both aerobic and resistance) regularly, watch out for foods with a high glycemic index, cut out sugars, caffeine, and alcohol, minimize your animal and large fish protein and fat consumption, avoid overly processed foods, eat lots of colorful vegetables high in antioxidants, get plenty of sleep, lower your stress, laugh, enjoy life. Yes, their plan will make you healthier if you can follow it. But their plan isn't any different from what most health books have been suggesting for at least a decade and most people haven't been following their advice. There is nothing *wrong* with this book and if you aren't familiar with modern diet, exercise, and nutrition advice it is a fine place to start. But if you are familiar with such things you won't find anything new in here that you can apply to your life.