Bought one of these for my Dad, 82, who is visually and hearing impaired. He loves this thing. I'm a huge Mac fan anyway because of the reliability and quality of these computers but whats nice for Dad is he's able to enlarge the screen to where he can read now whereas before, he couldn't. The audio is crisp and clear so he has no trouble understanding the audio.
The minimal real estate this takes up is fantastic and while the screen is large, it takes very little room on his desk. This is the third iMac we've bought over the years and I have to say that Apple never ceases to amaze me with their quality and design. Highly recommend this computer.
One comment and this really applies to all computers; be sure to max out the RAM. I do this as a rule of thumb for all computers and we put 4Gb on Dad's computer and it just screams!