Strange film, and at the same time, astonishing! I haven't read the book, but the movie is great. Definitely, not for everyone. This is one of those movies that make you think and reflect on issues of live an death. If you want a movie just for the sake of watching a movie, look elsewhere. There's No violence, no sex, no drugs, no killing sprees,no shootings, no terrorists, no bombs going off, no gore, no torn-out limbs, no cars crashing, etc, etc, etc. If this is what you are looking for, there's plenty of movies to choose from. This one is only for mature thinking people who comprehend psychological plots, end-of-live topics and the implications (and dangers) of screwing around with genes for "medical or therapeutical" purposes. It can be considered as a masterpiece on the bio-ethical implications of gene manipulation, and messing around with the natural order! If this is your kind of movie, I recommend also: "Mar Adentro", "Tuesdays with Morrie", "Wit" (although a tad boring), and "Godsend" I also recommend reading a book called "The private world of dying children" from Myra Bluebond-Langer. An excellent insight to how children percieve the end of their lives and all that goes around them from a bio-psycho-social and spiritual point of view. If you are a health care worker and especially working with kids with life threatening illnesses, this movie is a Must See. It is a well worth investment.